Manuscript Number : IJSRSET151591
Developments of HPLC Method for Determination of Methyl Dopa
Authors(1) :-Hussein Hassan Kharnoob
This research contains the development of accurate and quick method for determination methyldopa drug using high performance liquid chromatographic technique, injected 20 μl of the drug solution with concentration 20 μg/ml using a column type C18 , mobile phase consists of Acetonitrile: 0.02M KH2PO4 (70 : 30) at flow rate of 1.6 m1/min using UV detector at 275nm, pH5.65 ,with retention time 2.89min at linear range 10 – 50μg/ml with good accuracy and precision . The recovery value is to 99.2%and detection limit of 0.05 μg/ ml. The method is applied successfully to determine methyl dopa in its pharmaceutical formulations.
Hussein Hassan Kharnoob
Chromatography, Methy Dopa, Acetonitrile, Drug
Publication Details
Published in :
Volume 1 | Issue 6 | November-December 2015 Article Preview
College Pharmacy, Tikrit University, Tikrit, Iraq
Date of Publication :
2015-12-25
License: This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) :
22-28
Manuscript Number :
IJSRSET151591
Publisher : Technoscience Academy
Journal URL :
http://ijsrset.com/IJSRSET151591