Computational Techniques for the Functional Annotation of Hypothetical ORFS in Human Chromosome 3

Authors(2) :-Sivashankari Selvarajan, Piramanayagam Shanmughavel

In biochemistry, a hypothetical protein encoded by a hypothetical gene is a protein whose existence has been predicted, for which there is no experimental evidence for expression in vivo. As a result, the function of such genes is not known. Despite several efforts, only 50-60 % of genes have been annotated in most completely sequenced genomes and their functions are known. The rest 40% of the genes in any genome is totally unknown in terms of its functions. As of September 2010, there are around 637 genes encoded as Hypothetical in NCBI. So, the present investigation focused on functional annotation of hypothetical genes in the Chromosome 3 of the Human Genome.

Authors and Affiliations

Sivashankari Selvarajan
Assistant Professor in UGC, Innovative Programme, Department of Bioinformatics, Nirmala College for Women, Coimbatore, Tamil Nadu, India
Piramanayagam Shanmughavel
Associate Professor, Department of Bioinformatics, Bharathiar University, Coimbatore, Tamil Nadu, India

Annotation, Chromosome3, Function, Hypothetical Genes

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Publication Details

Published in : Volume 2 | Issue 2 | March-April 2016
Date of Publication : 2017-12-31
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 337-343
Manuscript Number : IJSRSET1622104
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Sivashankari Selvarajan, Piramanayagam Shanmughavel, " Computational Techniques for the Functional Annotation of Hypothetical ORFS in Human Chromosome 3, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 2, Issue 2, pp.337-343, March-April-2016.
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