Antimicrobial Susceptibility Pattern of Multidrug Resistant Uropathogens

Abstract

UTI is a common infection in community, more common in sexually active women. Now a days incidence of infection by multidrug resistant uropathogens is increasing worldwide. Consequently, area specific monitoring studies to document the microorganisms causing UTIs and their antimicrobial susceptibility is mandatory for helping the selection of an effective empirical treatment. Therefore, the present study was aimed at gaining knowledge about the type of pathogens responsible for and their susceptibility patterns at this area.

We studied 300 isolates in which 241(80.3%) were gram negative bacilli, 44(14.6%) were gram positive cocci and 15(5%) were candida spp. Most commonly isolated organism was E.coli followed by Klebsiella spp, Citrobacter spp  Enterobacter spp, Proteus spp, and Acinetobacter spp. In gram positive organism most common was staphylococci aureus, followed by enterococci spp, coagulase negative staphylococcus. In our study 23% were multi drug resistant. This percentage increase in klebsielllae spp 29% and E coli 24%. We did not found any pan drug resistant organism in our study.

In our study MDR were more found in IPD patients than OPD (61%). In MDR maximum resistant was seen to cephalosporines and amoxicillin/clvulanate while very less resistance to quinolones, netylmicin, gentamycin, piperacillin tazobactam and Imepenem.