Prevalence and Antibiogram of Pseudomonas aeruginosa in a Tertiary Care Hospital of Haryana

Authors(4) :-Sameena Khan, Ruby Naz, Ruchi Girotra, A K Malik

Pseudomonas aeruginosa (P. aeruginosa) is a well-known invasive pathogen that can frequently cause severe infections in hospitalized patients. A major problem with P. aeruginosa infection may be that this pathogen exhibits a high degree of resistance to broad spectrum antibiotics. The main aim of this study is to know the prevalence of P. aeruginosa infection and its antibiogram in a tertiary care hospital. A total of 100 isolates of P. aeruginosa were isolated from different clinical samples using standard conventional techniques for six months, from June 2015 to December 2015. Antibiotic susceptibility testing was done by using kirby -Bauer disc diffusion method as per CLSI guidelines. In our study, highest resistance was observed forCefuroxime (87%) and least resistance for Amikacin and Gentamicin (5% and14%) respectively. The most effective antibiotics were Colistin, Polymyxin B.

Authors and Affiliations

Sameena Khan
Demonstrator Microbiology, SHKM Govt Medical College and Hospital Nalhar, Mewat, Haryana, , India
Ruby Naz
Demonstrator Microbiology, SHKM Govt Medical College and Hospital Nalhar, Mewat, Haryana, , India
Ruchi Girotra
Demonstrator Microbiology, SHKM Govt Medical College and Hospital Nalhar, Mewat, Haryana, , India
A K Malik
Professor and Head of Department Microbiology, SHKM Govt Medical College and Hospital,Nalhar Mewat, Haryana, India

Antibiotics , Resistance, P. Aeruginosa

  1. Collee JG, Fraser AG, Marmion BP, Simmons A. Mackie and McCartney Practical Medical Microbiology. 14th ed. Edinburgh: Churchill Livingstone; 1996
  2. Ana Lucia Peixoto de Freitas and Afonso Luis Barth. Antibiotic resistance and molecular typing of pseudomonas aeruginosa : focus on imepenem Brazilian journal infectious disease 2002;6:1-7
  3. Alonso A, Campanario E, Martinez JL. Emergence of multidrug-resistant mutants is increased under antibiotic selective pressure in Pseudomonas aeruginosa Microbiology. 1999;145:2857-62.
  4. Bonomo RA, Szabo D. Mechanisms of multidrug resistance in Acinetobacter species and Pseudomonas aeruginosa. Clin Infect Dis 2006;43 (2): 49-56.
  5. Clinical and Laboratory Standards Institute, "Performance standards for antimicrobial disk susceptibility testing, " in Proceedings of the 17th International Supplement, vol. 21, Wayne, Ind, USA, M100-311, 2000
  6. Vijaya Chaudhari, Sandeep Gunjal, Mukesh Mehta. Antibiotic resistance patterns of Pseudomonas aeruginosa in a tertiary care hospital, in Central India. International Journal of Medical science and Public Health. 2013;2(2): 386-89
  7. OkonK O, Aguwe PC, Oladosu W, Balogun, Uba A, Antibiotic resistance patterns of Pseudomonas aeruginosa isolated from clinical specimens in a tertiary care hospital in Northeastern Nigeria. Journal of microbiology and antimicrobials. 2009;1(2):019-026.
  8. Siti Nur Atiquah Idris et al. Antimicrobial susceptibility pattern and distribution of EXO U and EXO S in clinical isolates of pseudomonas aeruginosa at a Malaysian hospital south east Asian Journal tropical medicine public health 2012;43:116-23
  9. Anupurba S, Battacharjee A, Garg A, Ranjansen M. The antimicrobial susceptibility of Psuedomonas aeruginosa isolated from wound infections. Indian J Dermatol. 2006; 51(4): 286-88.
  10. Rajat RM, Ninama G, Mistry K, Parmar R, Patel k, Vegad MM. Antibiotic resistance pattern in pseudomonas aeruginosa species isolated at a teriary care hospital, Ahmadabad, National journal of medical research 2012;2(2):156-159
  11. Ravichandra Prakash. Rashmi Belodu, Neena karangate, Suresh Sonth, Anitha. M. R, Vijayanath. Antimicrobial susceptibility pattern od Pseudomonas aeruginosa strains isolated from clinical sources. Journal of Pharmaceuticals and Biomedical Science, 2012;14(05):1-4

Publication Details

Published in : Volume 2 | Issue 1 | January-February 2016
Date of Publication : 2016-02-25
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 635-637
Manuscript Number : IJSRSET162475
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Sameena Khan, Ruby Naz, Ruchi Girotra, A K Malik, " Prevalence and Antibiogram of Pseudomonas aeruginosa in a Tertiary Care Hospital of Haryana, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 2, Issue 1, pp.635-637, January-February-2016.
Journal URL : http://ijsrset.com/IJSRSET162475

Follow Us

Contact Us