Effect of Ocimum Sanctum (Tulsi) on Serum Calcium And Serum Inorganic Phosphate Activities of Male Albino Rat

Authors

  • Sandhya Shah  Department of Zoology, Udai Pratap Autonomus College, Varanasi, Uttar Pradesh, India
  • S. R. Barai  Department of Zoology, Udai Pratap Autonomus College, Varanasi, Uttar Pradesh, India

Keywords:

Ocimum sanctum, Serum Calcium,Serum Inorganic  Phosphate,Male Albino Rats

Abstract

The aim of research study was undertaken to investigate the effect of different schedules of oral administration of tulsi(Ocimum sanctum)leaf on serum calcium and serum phosphate activities of male albino rats. Ocimum sanctum (1g/kg body weight) administration for 60 days in male albino rats on biochemical parameters weighing, between 100-150g obtained from the disease free stock of the animal house were used for the experiment of rats. The experiment was divided in control group and experimental group. Experimental rats were administered aqueous dose of Ocimum sanctum, and control rats received vehicle. Serum  parameters were recorded in male albino rats. Significant changes were observed in serum calcium and serum inorganic phosphate  activities (P<0.05) by days 60 of the Ocimum sanctum administration.

References

  1. Abdulrahman FI and OnyeyiliPA.(2001). Phytochemical activities of the stem bark of Terminaliaavicennoides. Bull. Anim. Health Prods.Afr.,49: 236-242.
  2. Anbarasu K, Vijayalakshmi G.( 2007) Improved shelf life of protein-rich tofu using Ocimum sanctum (Tulsi) extracts to benefit Indian rural population. J Food Sci. ;72:M300–05.
  3. Arfa,M.M. and Rashed A.M. (2008).The modulative biochemical effect of extract of ocimum gratissimum as anti- oxidant on diabetic albino rats,Egypt. J. Comp.Path. Vol.21 No. 3(sep);69-87.
  4. B.H., Khalil.D.A., Hollis,B.W. (2002). Soy proteins its effects on intestinal calcium transport, serum vitamin D, and insulin-like growth factor-I in ovaricctomized rats Calcil Tissue Int.70,483-488.
  5. J. Pros. A.1999 Calcium is a treatment of osteoporosis Drugs Today,35(8).631-639.
  6. Crenshaw TD,(2001) Calcium Phosphorus, Vitamin D, NAD Vitamin K in swine nutrition. In:Lewis AJ, Southern LL, EDITORS, Swine Nutrition. 2nd Ed.CRC Press; Boca Raton , Florida:2001pp.187-212.
  7. Deprez, X, Fardellone .P., 2003, Non pharmacological prevention of osteoporotic fracture.Joint Bones Spine,70(6),448-457.
  8. Flynn A., 2003.The role of dietary calcium in bone health, Pioc Nur Soc 62 (4),851-858.
  9. Gillespie JR. Minerals. In;Bruce MA, Haller C,(1987) editors. Animal Nutrition and Feeding. Dalmar Publishers Inc: Albany, New York.pp.53-75.
  10. Gayathri FAthima and Sheela Devi R.(2015).Effect of Ocimum sanctum on Noise Stress Changes in the Membrane Bound Enzymes of Albino Rats in Brain,World Journal of Pharmaceutical Sciences.2321-3310.
  11. Joshi, B.,S. Lekhak and A. Sharma(2009) Antimicribial property of different medicinal plants:Ocimum sanctum, Cinnamomum zeylanicum, Xanthorylum armatum and Origanum majorana.Kathmandu University.J.Sci.Eng.Technol.,5:143-150.
  12. Johs T and Duquette M. 1991. Deficiency of phosphorus in man AM. J. of clin. nutr: 53:448-456
  13. Kellems RO, Church DC. Nutrients: their metabolism feeding standards. In: Kellems RO, Church DC,editors. Livestosk Feeds and Feeing.4th ed. Prentice-Hall, Inc; PPER Saddle River, New Jersey: 1998.pp.16-39.
  14. Krishnaiah D, Sabatly R and Bono A.(2007) Phytochemical antioxidants for health and medicine . A move towards nature. Journal of molecular biology and biotechnology,1(4):97-104.
  15. Khan IZ.(1996). The role of chemistry in health, disease and aging.A Seminar paper presented in the Department of Chemistry,University of Maiduguri.
  16. Linder and Manria, C (1991), Nutritional biochemistry and metabolism with clinical applications.Appleton and Lange, Norwalk, 2:191-212.
  17. Mann,C.M., C.D. Cox and J.l. Markham,(2000) The outer membrane of Psuedomonas aerginosa NCTC 6749 Contributes to its lolerance to the essential oil of Melaleuca alternifolia ( tea tree oil). Lett. Applied Microbiol., 30: 294-297.
  18. Mirheidar, H.,( 1990)Herbal Knowledge. Ist Edn., Islamic Culture Publication, USA.
  19. Moriira,M.R. et al.,(2005). Inhibitory parameters of essential oils to reduce a foodborne pathogen.LWT Food Sci, Technol,Mar del Piata,38(5),565-570.
  20. Moses EA, Ogugbuaja VO and OgarawuVC.(2002) Enrichment of element of Nigerian bituminous coal fly ash and their effects on hematological parameters of exposed rabbits . Nig.J.Exp.Applied Biol.,3;95-100.
  21. Nadkarni KM.( 1976) Indian Material Medica,Popular Prakashan, Bombay,.pp.861.
  22. NIIR Board, National institute of industrial research (India) Compendium of medicinal Plants.2004.National Institute of Industrial research.2004:320.
  23. Ogugbuaja VO, Akinniyi JA,Abdulrahman FI and OgarawuVC.(1997). Elemental contents of medicinal plants. A monograph, Department of Chemistry,faculty of science, University of Maidugri,Nigeria.
  24. Prabakaran M, Merinal S and Panneerselvam A.(2011) Investigation of Phylloplanemycoflora from some medicinal plants. European Journal of Experimental Biology, ;1(2): 215-219.
  25. Poonam Mishra and Sanjay Mishra(2011) Study of Antibacterial Activity of Ocimum sanctum Extract Against Gram Positive and Gram Negative Bacteria,American Journal of Food Technology6 (4): 336-341.
  26. Caroline Jeba et. al. (2011) Immunomodulatory activity of aqueous extract of Ocimum sanctum in rat, International Journal on Pharmaceutical and Biomedical Research (IJPBR) Vol.2 (1), 33-38.
  27. Sarang Jain and Ameeta Argal.(2013). Effect of a polyherbal formulation on glycolic acid- induced urolithasis in rats, Bulletin of Pharmaceutical Research; 3(1): 40-3.
  28. Siva M., Shanmugam KR, Shanmugam B,Venkata G.,Ravi S., Sthyavelu Rddy K., Mallikarjuna K.,(2016) Ocimum sanctum a review on the pharmacological properties.International Journal of Basic & Clinical Pharmacology.
  29. Sikmon,J.E., M.R. Morales, W.B. Phippen, R.F. Vieira and Z.Hao,(1990) Perspectives on New Crops and New Uses. In: A source of Aroma Compounds and a Popular Curlinary and Ornamental Herbs, Janick, J.(Ed.). ASHS Press, Alexander, VA., pp:495-505.
  30. Shute KH. The Biological of trace elements their role in nutrition. Philadelphia (USA);JB Lippincot co.,1964.
  31. Sarang Jain and Ameeta Argal.2013 effect of a polyherbal formulation on gycolic acid induced urolthiasis in rats,Bulletin of Pharmaceutical Research;3(1): 40-3.
  32. Volak, J. and S. Jiri,(1997) Plants Medicinales Interpreter.3rd Edn., Thran University Publictions, Tehran,pp:20.
  33. Varalakshmi P, Shamila Y, Latha E.(1990). Effect of Crataeva nurvala in experimental urolithiasis J. Ethnopharmacol.;28(3);313-21.
  34. 1996 ,Trace elements in human Nnutrition and Health. World health organization,Geneva.
  35. Zagari,A., (1990).Medicinal Plants. 4th Edn., Tehran University Press, Thran, pp:1-57.

Downloads

Published

2016-10-30

Issue

Section

Research Articles

How to Cite

[1]
Sandhya Shah, S. R. Barai, " Effect of Ocimum Sanctum (Tulsi) on Serum Calcium And Serum Inorganic Phosphate Activities of Male Albino Rat, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 2, Issue 5, pp.273-277, September-October-2016.