Molecular detection of parvovirus B19 in positive hepatitis B in haemodialysis patients in Khartoum State, Sudan

Authors(4) :-Hadeel H E Lmahal, Khalid A Enan, Abdel Rahim M. El Hussein, Aymen Abdelhaleem

Background: Human parvovirus B19 has been identified in the serum of hepatitis B virus infected patient. It mostly cause erythema infectiosum in children but can also cause hydrops fetalis, arthropathies and transient aplastic crisis in adults.
Methods: The aim of this study was to determine the prevalence of B19-DNA in positive hepatitis B heamodialysis infected Sudanese patients. Serum samples from 50 heamodialysis HBV infected patients and 34 healthy donations were collected and analyzed for the presence of B19-DNA by nested PCR.
Result: 34 (11%) of healthy donors showed B19-DNA in nested PCR while 50 HBV heamodialysis patient showed the infection.
Conclusion: Our findings suggest that human parvovirus B19 had higher prevalence among hepatitis B virus infected patients. Further investigation is needed to clarify if such infections can serious by affect patient health.

Authors and Affiliations

Hadeel H E Lmahal
Department of Microbiology, Faculty of Medical Laboratory Sciences El Nellin University, Sudan
Khalid A Enan
Department of Virology, Central Laboratory, The Ministry of Higher Education and Scientific Research, Khartoum, Sudan
Abdel Rahim M. El Hussein
Medical research center, Jazan University, Jazan Saudi Arabia
Aymen Abdelhaleem
Department of Microbiology and Parasitology, Faculty of Medicine, University of Khartoum, P.O. Box: 8067, Khartoum, Sudan

Parvovirus B19, PCR, Sudan

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Publication Details

Published in : Volume 3 | Issue 5 | July-August 2017
Date of Publication : 2017-08-31
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 80-84
Manuscript Number : IJSRSET1733152
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Hadeel H E Lmahal, Khalid A Enan, Abdel Rahim M. El Hussein, Aymen Abdelhaleem, " Molecular detection of parvovirus B19 in positive hepatitis B in haemodialysis patients in Khartoum State, Sudan, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 5, pp.80-84, July-August-2017.
Journal URL : http://ijsrset.com/IJSRSET1733152

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