Molecular detection of parvovirus B19 in positive hepatitis B in haemodialysis patients in Khartoum State, Sudan

Authors

  • Hadeel H E Lmahal  Department of Microbiology, Faculty of Medical Laboratory Sciences El Nellin University, Sudan
  • Khalid A Enan  Department of Virology, Central Laboratory, The Ministry of Higher Education and Scientific Research, Khartoum, Sudan
  • Abdel Rahim M. El Hussein  Medical research center, Jazan University, Jazan Saudi Arabia
  • Aymen Abdelhaleem  Department of Microbiology and Parasitology, Faculty of Medicine, University of Khartoum, P.O. Box: 8067, Khartoum, Sudan

Keywords:

Parvovirus B19, PCR, Sudan

Abstract

Background: Human parvovirus B19 has been identified in the serum of hepatitis B virus infected patient. It mostly cause erythema infectiosum in children but can also cause hydrops fetalis, arthropathies and transient aplastic crisis in adults.
Methods: The aim of this study was to determine the prevalence of B19-DNA in positive hepatitis B heamodialysis infected Sudanese patients. Serum samples from 50 heamodialysis HBV infected patients and 34 healthy donations were collected and analyzed for the presence of B19-DNA by nested PCR.
Result: 34 (11%) of healthy donors showed B19-DNA in nested PCR while 50 HBV heamodialysis patient showed the infection.
Conclusion: Our findings suggest that human parvovirus B19 had higher prevalence among hepatitis B virus infected patients. Further investigation is needed to clarify if such infections can serious by affect patient health.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2017-08-31

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Volume 3, Issue 5, July-August-2017

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Research Articles

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[1]
Hadeel H E Lmahal, Khalid A Enan, Abdel Rahim M. El Hussein, Aymen Abdelhaleem, " Molecular detection of parvovirus B19 in positive hepatitis B in haemodialysis patients in Khartoum State, Sudan, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 5, pp.80-84, July-August-2017.