Synthesis and Antimicrobial Evaluation of Novel Coumarin derivatives Bearing Piperidinyl Substituent

Authors

  • Bhavin Thaker  Department of Chemistry, Pacific College of Basic & Applied Sciences, Udaipur, Rajasthan, India
  • Kartik Vyas  Department of Chemistry, Sheth L.H. Science College, Mansa, Gujarat, India
  • Janak Shukla  C.N.P.F Arts and D.N. Science College, Dabhoi, Gujarat, India
  • Kiran Nimavat  Department of Chemistry, Government Science College, Gandhinagar, Gujarat, India

Keywords:

Coumarins, Piperidinyl Substituent, Antibacterial activity, Antifungal activity

Abstract

Novel 3-((E)-3-(aryl)-3-oxoprop-1-enyl)-4-(piperidin-1-yl)-2H-chromen-2-ones were synthesized by the reaction of 2-oxo-4-(piperidin-1-yl)-2H-chromene-3-carbaldehyde with different acetophenones in presence of piperidine. All the newly synthesized compounds were characterized by different spectroscopic techniques and elemental analyses. All the compounds were evaluated for their antibacterial activity against S. aureus, E.coli and for their antifungal activity against C. albicans.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2017-08-31

Issue

Volume 3, Issue 5, July-August-2017

Section

Research Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Bhavin Thaker, Kartik Vyas, Janak Shukla, Kiran Nimavat, " Synthesis and Antimicrobial Evaluation of Novel Coumarin derivatives Bearing Piperidinyl Substituent, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 5, pp.601-603, July-August-2017.