Synthesis and Antimicrobial Evaluation of Novel Chalcones Bearing Coumarin Moiety

Authors(5) :-Bhavin Thaker, Kartik Vyas, Janak Shukla, Ramesh Patel, Kiran Nimavat

Novel Chalcones bearing Coumarin moiety were synthesized by the reaction of 2-oxo-4-(piperazin-1-yl)-2H-chromene-3-carbaldehyde with different acetophenones in presence of piperidine. All the newly synthesized chalcones were characterized by different spectroscopic techniques and elemental analyses. All the compounds were evaluated for their antibacterial activity against S. aureus, E.coli and for their antifungal activity against C. albicans.

Authors and Affiliations

Bhavin Thaker
Department of Chemistry, Pacific College of Basic & Applied Sciences, Udaipur, Rajasthan, India
Kartik Vyas
Department of Chemistry, Sheth L.H. Science College, Mansa, Gujarat, India
Janak Shukla
Department of Chemistry, C. U. Shah Science College, Ahmedabad, Gujarat, India
Ramesh Patel
C.N.P.F Arts and D.N. Science College, Dabhoi, Gujarat, India
Kiran Nimavat
Department of Chemistry, Government Science College, Gandhinagar, Gujarat, India

Chalcones, Coumarin Moiety, Antibacterial Activity, Antifungal Activity

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Publication Details

Published in : Volume 3 | Issue 5 | July-August 2017
Date of Publication : 2017-08-31
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 643-645
Manuscript Number : IJSRSET1734161
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Bhavin Thaker, Kartik Vyas, Janak Shukla, Ramesh Patel, Kiran Nimavat, " Synthesis and Antimicrobial Evaluation of Novel Chalcones Bearing Coumarin Moiety, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 5, pp.643-645, July-August-2017.
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