Synthesis Characterization and Anti-Inflammatory Activities of Substituted Aniline Oxadiazolyl Derivatives

Authors

  • Bhupender Singh Rawat  Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India
  • Shrawan Kumar Shukla  Department of Plastic Technology, H.B.T.I., Kanpur, Uttar Pradesh, India
  • Nidhi Gangwar  Department of Chemistry, G.B.P.U.A &T Pantnagar, Uttarakhand, India
  • Roopali Tandon  Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India
  • S. C Mehra   Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India

Keywords:

Oxadiazole, Antifungal, Antibacterial, Anti-Inflammatory Activity

Abstract

Oxadiazoles are an important class of bioactive and industrially important organic compounds with diverse pharmacological activities such as antibacterial, anthelmintic, antifungal, Anti-inflammatory etc. oxadiazole derivatives have been studied in the past few decades. It is a five membered heterocyclic structure and exist in four isomeric forms out of its four isomers 1, 3, 4- oxadiazole exhibited a wide range of biological activities . In the present work isomeric forms of ortho/meta/ para toluidine, is converted to 3- methyl-N-(5- substituted phenyl)-1, 3, 4 oxadiazol-2yl-methyl aniline. The synthesized compounds were investigated for anti-inflammatory activities.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2017-08-31

Issue

Volume 3, Issue 5, July-August-2017

Section

Research Articles

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How to Cite

[1]
Bhupender Singh Rawat, Shrawan Kumar Shukla, Nidhi Gangwar, Roopali Tandon, S. C Mehra , " Synthesis Characterization and Anti-Inflammatory Activities of Substituted Aniline Oxadiazolyl Derivatives, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 5, pp.290-295, July-August-2017.