Synthesis Characterization and Anti-Inflammatory Activities of Substituted Aniline Oxadiazolyl Derivatives

Authors(5) :-Bhupender Singh Rawat, Shrawan Kumar Shukla, Nidhi Gangwar, Roopali Tandon, S. C Mehra

Oxadiazoles are an important class of bioactive and industrially important organic compounds with diverse pharmacological activities such as antibacterial, anthelmintic, antifungal, Anti-inflammatory etc. oxadiazole derivatives have been studied in the past few decades. It is a five membered heterocyclic structure and exist in four isomeric forms out of its four isomers 1, 3, 4- oxadiazole exhibited a wide range of biological activities . In the present work isomeric forms of ortho/meta/ para toluidine, is converted to 3- methyl-N-(5- substituted phenyl)-1, 3, 4 oxadiazol-2yl-methyl aniline. The synthesized compounds were investigated for anti-inflammatory activities.

Authors and Affiliations

Bhupender Singh Rawat
Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India
Shrawan Kumar Shukla
Department of Plastic Technology, H.B.T.I., Kanpur, Uttar Pradesh, India
Nidhi Gangwar
Department of Chemistry, G.B.P.U.A &T Pantnagar, Uttarakhand, India
Roopali Tandon
Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India
S. C Mehra
Department of Chemistry, Bareilly College, Bareilly, Uttar Pradesh, India

Oxadiazole, Antifungal, Antibacterial, Anti-Inflammatory Activity

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Publication Details

Published in : Volume 3 | Issue 5 | July-August 2017
Date of Publication : 2017-08-31
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 290-295
Manuscript Number : IJSRSET173467
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Bhupender Singh Rawat, Shrawan Kumar Shukla, Nidhi Gangwar, Roopali Tandon, S. C Mehra , " Synthesis Characterization and Anti-Inflammatory Activities of Substituted Aniline Oxadiazolyl Derivatives, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 5, pp.290-295, July-August.2017
URL : http://ijsrset.com/IJSRSET173467

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