Effectual direct synthesis of diversely substituted 4-aryl/alkyl coumarins by palladium catalyzed oxidative Suzuki–Miyaura coupling

Authors(3) :-Jaydip Rajpara, Arpit Radadia, Yogesh Naliapara

An effectual direct synthesis of 4-aryl/alkyl substituted coumarin was developed using a palladium-catalyzed oxidative Suzuki–Miyaura coupling reaction strategy. Use of Pd2(dba)3 in the presence of Na2CO3 in THF solvent was found to be the most effective reaction condition for excellent yield.

Authors and Affiliations

Jaydip Rajpara
Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot, India
Arpit Radadia
Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot, India
Yogesh Naliapara
Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot, India

4-aryl/alkylcoumarins, Suzuki-Miyaura coupling, Palladium catalyst, Boronic acid or

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Publication Details

Published in : Volume 3 | Issue 6 | September-October 2017
Date of Publication : 2017-10-31
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 230-237
Manuscript Number : IJSRSET173646
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Jaydip Rajpara, Arpit Radadia, Yogesh Naliapara, " Effectual direct synthesis of diversely substituted 4-aryl/alkyl coumarins by palladium catalyzed oxidative Suzuki–Miyaura coupling, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 6, pp.230-237, September-October-2017.
Journal URL : http://ijsrset.com/IJSRSET173646

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