Bulk Screening of Medicinal Plants and their Antitrypanosomal Activity

Authors(5) :-Gana James, Adekojo Solomon Adeolu, Danwake Jibrin Garba, Abubakar Baman Mohammed, Shaba Peter

The recent resistance to available trypanocids and by trypanosomes had hampered effective treatment and control. Herbal medicine has attracted much attention as potential therapeutic agent in the prevention and management of parasitic and infectious diseases, as they can yield potential leads to address emerging infections and resistance, indeed, the use of medicinal plant in treatment and management of human and animal diseases has been practiced before the advent of chemotherapy. The studied were carried by harvested fresh different parts of medicinal plants (leaves, stem, fruit, bark and root) and identified appropriately and processed accordingly. Nigerian medicinal plants were screened for possible anti-trypanosomal activity that could be further work on for isolation of trypanocidal compounds that may hold the key for development of new trypanocides and screen bulk of medicinal plants via in vitro media. In this current research on antitrypanosomal, from medicinal plants, out of the medicinal plants, Annona senegalensis (leaves, stem and roots), Terminalia avorensis and vitexdoriana displayed varied moderate to higher antitrypanosomal activity than other medicinal plant screened. The varied antitrypanosomal activity in this research report which ranged from immobilization to complete killing of the trypanosomes are comparable to trypanocidal activityof comparative invitrotrypanocidal activities of petroleum ether, chloroform, methanol and aqueous extracts of some Nigerian savannah plants. The finding indicates that few of the medicinal plants screened contained trypanocidal compound(s), if isolated in further research could be a promising candidate for a future trypanocide.

Authors and Affiliations

Gana James
Federal College of Education, School of Vocational Education Department of agricultural education, P.M.B 39, Kontagora Niger state, Nigeria
Adekojo Solomon Adeolu
Federal College of Education, School of Vocational Education Department of agricultural education, P.M.B 39, Kontagora Niger state, Nigeria
Danwake Jibrin Garba
Federal College of Education, School of Vocational Education Department of agricultural education, P.M.B 39, Kontagora Niger state, Nigeria
Abubakar Baman Mohammed
Federal College of Education, School of Vocational Education Department of agricultural education, P.M.B 39, Kontagora Niger state, Nigeria
Shaba Peter
Niger state College of Agriculture, Department of Animal Health and Production Technology. P.M.B. 109, Mokwa, Nigeria

Medicinal Plants, Antitrypanosomal , Trypanosomal, Trypanocidal.

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Publication Details

Published in : Volume 4 | Issue 10 | September-October 2018
Date of Publication : 2018-10-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 211-224
Manuscript Number : IJSRSET1841051
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Gana James, Adekojo Solomon Adeolu, Danwake Jibrin Garba, Abubakar Baman Mohammed, Shaba Peter, " Bulk Screening of Medicinal Plants and their Antitrypanosomal Activity, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 10, pp.211-224, September-October.2018
URL : http://ijsrset.com/IJSRSET1841051

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