Synthesis, Characterization and Antimicrobial activity (MIC) of some substituted pyranopyrazole derivatives.

Authors(3) :-Hitesh B. Vala1, Jatin Upadhayay, Cheatana Rajyaguru

Synthesis of 4-(3-(4-chlorophenyl)-1 phenyl-1H pyrazol-4-yl)3,5-dimethyl 4,7-dihydro 1H-pyrano[2,3-c;6,5-c,] dipyrazole by well-known knoevenagel condensation reaction of 3-methyl pyrazole 5-one and 3-(4-chlorophenyl)-1-phenyl-1H pyrazole 4-carbaldehyde in presence of piperidine as catalyst and acetonitrile as solvent. Various pyrazolecarbaldehyde were synthesized from substituted acetophenone and phenyl hydrazine reaction and followed by vilsmier hack reaction. We synthesized different substituted pyrazolecarbaldehyde. The constitution of all the synthesized compounds has been characterized by using IR, MASS 1H NMR spectroscopy. All synthesized compounds were screened for their antimicrobial activity.

Authors and Affiliations

Hitesh B. Vala1
GSFC LTD, Baroda, Gujarat, India
Jatin Upadhayay
MVM science college, Rajkot, Gujarat, India
Cheatana Rajyaguru

Knoevenagel condensation, 3-methyl pyrazole 5-one, vilsmier hack reaction, pyrazolecarbaldehyde, piperidine, acetonitrile.

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Publication Details

Published in : Volume 4 | Issue 1 | January-February 2018
Date of Publication : 2018-02-28
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 796-800
Manuscript Number : IJSRSET1841218
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Hitesh B. Vala1, Jatin Upadhayay, Cheatana Rajyaguru, " Synthesis, Characterization and Antimicrobial activity (MIC) of some substituted pyranopyrazole derivatives., International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 1, pp.796-800, January-February-2018.
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