Synthesis, Characterization and Antimicrobial Analysis Of Various Substituted 6-(3-(5-Bromothiophen-2-Yl)-1-Phenyl-1H-Pyrazol-4-Yl)-4-(2-Hydroxyphenyl) Pyrimidine-2(1H)-Thiones

Authors(4) :-Sunil S. Bhagat, Balaji D. Rupnar, Amol J. Shirsat, Charansingh H. Gill

The title compounds thiopyrimidines 3(a-h) have been synthesized from chromones 1(a-h) by refluxing thiourea 2 with potassium hydroxide. The structures of all newly synthesized compounds have been confirmed by IR, 1H NMR and Mass spectral data. The synthesized compounds have been screened for their antimicrobial activity. Some of the compounds show moderate antimicrobial activity as compared to the reference drugs Ciprofloxacin and Fluconazole.

Authors and Affiliations

Sunil S. Bhagat
Department of Chemistry, R. B. Attal Arts, Science and Commerce College, Georai,Beed, Maharashtra, India
Balaji D. Rupnar
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India
Amol J. Shirsat

Charansingh H. Gill

Chromones, Pyrazolopyrimidines, Antimicrobial Activity

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Publication Details

Published in : Volume 4 | Issue 3 | January-February 2018
Date of Publication : 2018-01-22
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 01-03
Manuscript Number : IJSRSET184301
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Sunil S. Bhagat, Balaji D. Rupnar, Amol J. Shirsat, Charansingh H. Gill, " Synthesis, Characterization and Antimicrobial Analysis Of Various Substituted 6-(3-(5-Bromothiophen-2-Yl)-1-Phenyl-1H-Pyrazol-4-Yl)-4-(2-Hydroxyphenyl) Pyrimidine-2(1H)-Thiones, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 3, pp.01-03, January-February.2018
URL : http://ijsrset.com/IJSRSET184301

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