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Synthesis, Characterization and Antimicrobial Analysis Of Various Substituted 6-(3-(5-Bromothiophen-2-Yl)-1-Phenyl-1H-Pyrazol-4-Yl)-4-(2-Hydroxyphenyl) Pyrimidine-2(1H)-Thiones


Sunil S. Bhagat, Balaji D. Rupnar, Amol J. Shirsat, Charansingh H. Gill
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The title compounds thiopyrimidines 3(a-h) have been synthesized from chromones 1(a-h) by refluxing thiourea 2 with potassium hydroxide. The structures of all newly synthesized compounds have been confirmed by IR, 1H NMR and Mass spectral data. The synthesized compounds have been screened for their antimicrobial activity. Some of the compounds show moderate antimicrobial activity as compared to the reference drugs Ciprofloxacin and Fluconazole.

Sunil S. Bhagat, Balaji D. Rupnar, Amol J. Shirsat, Charansingh H. Gill

Chromones, Pyrazolopyrimidines, Antimicrobial Activity

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Publication Details

Published in : Volume 4 | Issue 3 | January-February - 2018
Date of Publication Print ISSN Online ISSN
2018-01-22 2395-1990 2394-4099
Page(s) Manuscript Number   Publisher
01-03 IJSRSET184301   Technoscience Academy

Cite This Article

Sunil S. Bhagat, Balaji D. Rupnar, Amol J. Shirsat, Charansingh H. Gill, "Synthesis, Characterization and Antimicrobial Analysis Of Various Substituted 6-(3-(5-Bromothiophen-2-Yl)-1-Phenyl-1H-Pyrazol-4-Yl)-4-(2-Hydroxyphenyl) Pyrimidine-2(1H)-Thiones", International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 3, pp.01-03, January-February-2018.
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