Manuscript Number : IJSRSET184301
Synthesis, Characterization and Antimicrobial Analysis Of Various Substituted 6-(3-(5-Bromothiophen-2-Yl)-1-Phenyl-1H-Pyrazol-4-Yl)-4-(2-Hydroxyphenyl) Pyrimidine-2(1H)-Thiones
Authors(4) :-Sunil S. Bhagat, Balaji D. Rupnar, Amol J. Shirsat, Charansingh H. Gill
The title compounds thiopyrimidines 3(a-h) have been synthesized from chromones 1(a-h) by refluxing thiourea 2 with potassium hydroxide. The structures of all newly synthesized compounds have been confirmed by IR, 1H NMR and Mass spectral data. The synthesized compounds have been screened for their antimicrobial activity. Some of the compounds show moderate antimicrobial activity as compared to the reference drugs Ciprofloxacin and Fluconazole.
Sunil S. Bhagat
Chromones, Pyrazolopyrimidines, Antimicrobial Activity
Publication Details
Published in :
Volume 4 | Issue 3 | January-February 2018 Article Preview
Department of Chemistry, R. B. Attal Arts, Science and Commerce College, Georai,Beed, Maharashtra, India
Balaji D. Rupnar
Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India
Amol J. Shirsat
Charansingh H. Gill
Date of Publication :
2018-01-22
License: This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) :
01-03
Manuscript Number :
IJSRSET184301
Publisher : Technoscience Academy
Journal URL :
https://ijsrset.com/IJSRSET184301