Synthesis and Characterization of Impurities Listed in United States Pharmacopeia of Risperidone Tablets

Authors(6) :-Laki Magar, Bhaskar H. Zaware, Brajesh Sharma, Kishor R. More, Kailas Shikhare, Leena Gupta

A very simple and efficient synthesis of three impurities of Risperidone tablets named Risperidone-cis-N-oxide, Risperidone-trans-N-oxide and Bicyclorisperidone mentioned in Unites States Pharmacopeia (USP) of Risperidone tablets has been presented in this manuscript. These three impurities were synthesized and fully characterized on the basis of mass, proton and carbon spectra.

Authors and Affiliations

Laki Magar
Department of chemistry, New Arts, Commerce and Science college, Ahmednagar, Maharashtra, India
Bhaskar H. Zaware
IPCA Laboratories Ltd. Chemical Research Division, Kandivali Industrial Estate,Kandivali (West). Mumbai, Maharashtra, India
Brajesh Sharma

Kishor R. More

Kailas Shikhare

Leena Gupta

Risperidone N-oxide, Bicyclorisperidone, Impurities, Synthesis.

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Publication Details

Published in : Volume 4 | Issue 3 | January-February 2018
Date of Publication : 2018-01-22
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 19-22
Manuscript Number : IJSRSET184306
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Laki Magar, Bhaskar H. Zaware, Brajesh Sharma, Kishor R. More, Kailas Shikhare, Leena Gupta, " Synthesis and Characterization of Impurities Listed in United States Pharmacopeia of Risperidone Tablets, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 3, pp.19-22, January-February.2018
URL : http://ijsrset.com/IJSRSET184306

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