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Synthesis of Some Novel Chlorochromones Containing Pyrazole Moiety


Amol J. Shirsat, Sunil S. Bhagat, Balaji D. Rupnar, Gopal K. Kakade
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A mild and proficient method has been developed for the synthesis of chlorochromones from oxidative cyclization of chalcones. High yield, simple workup procedure and mild reaction condition are main feature of this method. All synthesized chlorochromones has been evaluated for their antimicrobial activity against Gram +ve and Gram –ve microorganisms.

Amol J. Shirsat, Sunil S. Bhagat, Balaji D. Rupnar, Gopal K. Kakade

Chalcones, Chlorochromones, Antimicrobial, Gram +Ve And Gram –Ve Microorganisms.

  1. Wiley P F; J Am Chem Soc,4 (1952) 4329.
  2. Jongerbreur G; Arch Intern Pharmacodynamic,90 (1952) 384. b) Schmitz J,Hirt R,Eichenberger F E and Lavener H H; Helv Chim Acta 36 (1953) 620. c) Wander A G; Brit Pat,27 (1955) 4329.
  3. Donnelly D,Geoghegen R,Brein O,Phibin E and Wheeler T S; J Med Chem,8 (6) (1965) 872.
  4. Kelly D. R.,Carroff E.,Lood R. W. F.,Heal W. and Roberts S. M.,Chem Commun,2004; 2016.
  5. Sam Solomon W. D.,Ravi T. K. and Annadurai K.,Indian Drugs,1999; 36(7),466.
  6. Mokle SS,Sayeed MA,Kothawar C. Synthesis and antimicrobial activity of some chalcone derivatives. International Journal of Chemical Sciences 2004; 2 (1): 96-100.
  7. Gammill R. B.,Synthesis,1979; 901.
  8. Randhavane P,Karale B. Synthesis and biological screening of some fluorinated dibenzofuran containing 3- chlorochromones and benzothiazepines. Journal of Heterocyclic Chemistry 2009; 46(4): 732-736.
  9. Madje B R,Shindalkar S. S.,Ware M. N. and Shingare M. S.,Arkivoc,2005; 14,82.
  10. Gerwick W. H.,Lopez A.,Van Duyne G. D.,Clardy J.,Ortiz W. and Buez A.,Tetrahedron Lett,1979; 270,1986.

Publication Details

Published in : Volume 4 | Issue 3 | January-February - 2018
Date of Publication Print ISSN Online ISSN
2018-01-22 2395-1990 2394-4099
Page(s) Manuscript Number   Publisher
40-42 IJSRSET184311   Technoscience Academy

Cite This Article

Amol J. Shirsat, Sunil S. Bhagat, Balaji D. Rupnar, Gopal K. Kakade, "Synthesis of Some Novel Chlorochromones Containing Pyrazole Moiety", International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 3, pp.40-42, January-February-2018.
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