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Studies on Mangenese (II), Cobalt(II), Nickel(II), Copper(II) and Zn(II) complexes of substituted phenyl-thiazolyl-thiosemicarbazide


N. G. Kolhe, J. K. Khedkar, Y. H. Deshpande
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Thiazolyl thiosemicarbazide consists of a thiazole moiety in the structure. The compounds belonging to the thiazole ring systems have shown considerable activity in various fields including medicinal chemistry. Vitamin B1, sulphatiazole, promizole, nitridazole, aminitrazole, and thiabendazole, all contain thiazole ring in one form or other. Thiosemicarbazide containing –NCS group are known to possess pronounced biological activities. Thiosemicarbazide along with thiosemicarbazones have been used in various life saving drugs and drug action of these compounds was found to have been increased when administered in the form of their metal complexes. However a survey of literature reveals that no work has been done with substituted thiazolyl thiosemicarbazides. In the present work we investigate the complex formation process between some substituted thiazolyl thiosemicarbazides synthesised in our laboratory for the first time and various metal ions belonging to transition and inner transition series. The stability of different complexes follows the order: Mn < Co < Ni < Cu > Zn.

N. G. Kolhe, J. K. Khedkar, Y. H. Deshpande

Thiazolyl Thiosemicarbazide, Metal Ions, Metal-Ligand Complexes, Stability, Thermodynamics

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Publication Details

Published in : Volume 4 | Issue 3 | January-February - 2018
Date of Publication Print ISSN Online ISSN
2018-01-22 2395-1990 2394-4099
Page(s) Manuscript Number   Publisher
54-57 IJSRSET184314   Technoscience Academy

Cite This Article

N. G. Kolhe, J. K. Khedkar, Y. H. Deshpande, "Studies on Mangenese (II), Cobalt(II), Nickel(II), Copper(II) and Zn(II) complexes of substituted phenyl-thiazolyl-thiosemicarbazide", International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 3, pp.54-57, January-February-2018.
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