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A Glycerol Mediated Green Approach Towards the Synthesis of 1-H Indazole

Authors(5):

A. J. Dhole, T. S. Thopate, D. R. Thube, B.B.Jambe, J. S. Tikone
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An efficient green approach for the synthesis of Indazole using Glycerol as solvent has been reported. Silica supported sulphuric acid is reusable green catalyst and glycerol is found to be non-toxic and green solvent.No further purification is required.Substituted Compound 1 on stirring with hydrazine 2in presence of Glycerol gavecompound 3 with excellent yield. The structures of all the synthesized compounds have been confirmed by spectroscopic techniques.

A. J. Dhole, T. S. Thopate, D. R. Thube, B.B.Jambe, J. S. Tikone

o-hydroxyl Aldehyde/Ketone,SSA,Glycerol

Publication Details

Published in : Volume 4 | Issue 3 | January-February - 2018
Date of Publication Print ISSN Online ISSN
2018-01-22 2395-1990 2394-4099
Page(s) Manuscript Number   Publisher
66-66 IJSRSET184317   Technoscience Academy

Cite This Article

A. J. Dhole, T. S. Thopate, D. R. Thube, B.B.Jambe, J. S. Tikone, "A Glycerol Mediated Green Approach Towards the Synthesis of 1-H Indazole", International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 3, pp.66-66, January-February-2018.
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