A Glycerol Mediated Green Approach Towards the Synthesis of 1-H Indazole

Authors(5) :-A. J. Dhole, T. S. Thopate, D. R. Thube, B.B.Jambe, J. S. Tikone

An efficient green approach for the synthesis of Indazole using Glycerol as solvent has been reported. Silica supported sulphuric acid is reusable green catalyst and glycerol is found to be non-toxic and green solvent.No further purification is required.Substituted Compound 1 on stirring with hydrazine 2in presence of Glycerol gavecompound 3 with excellent yield. The structures of all the synthesized compounds have been confirmed by spectroscopic techniques.

Authors and Affiliations

A. J. Dhole
Department of Chemistry, New Arts, Commerce and Science College, Parner Ahmednagar, Maharashtra, India
T. S. Thopate
Department of Chemistry, New Arts, Commerce and Science College, Parner Ahmednagar, Maharashtra, India
D. R. Thube
Department of Chemistry, New Arts, Commerce and Science College, Parner Ahmednagar, Maharashtra, India
B.B.Jambe
Department of Chemistry, New Arts, Commerce and Science College, Parner Ahmednagar, Maharashtra, India
J. S. Tikone
Department of Chemistry, New Arts, Commerce and Science College, Parner Ahmednagar, Maharashtra, India

o-hydroxyl Aldehyde/Ketone,SSA,Glycerol

Publication Details

Published in : Volume 4 | Issue 3 | January-February 2018
Date of Publication : 2018-01-22
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 66-66
Manuscript Number : IJSRSET184317
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

A. J. Dhole, T. S. Thopate, D. R. Thube, B.B.Jambe, J. S. Tikone, " A Glycerol Mediated Green Approach Towards the Synthesis of 1-H Indazole, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 3, pp.66-66, January-February.2018
URL : http://ijsrset.com/IJSRSET184317

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