Molecular Detection of Human Herpes virus type 7 (HHV-7) among Renal Transplant Patients in Khartoum State, Sudan
Keywords:
Human herpes Viruses type 7(HHV-7).Abstract
Background:
Human herpesvirus 7 (HHV-7) is one of eight known members of the Herpesviridae family that infects humans. HHV-7is a member of Betaherpesviridae, a subfamily of the Herpesviridae that also includes HHV-6 and Cytomegalovirus (HHV-5 or HCMV).[1] HHV-7 often acts together with HHV-6, and the viruses together are sometimes referred to by their genus, Roseolovirus. HHV-7 was first isolated in 1990 from CD4+ T cells taken from peripheral blood lymphocytes. This study was carried out to detect the HHV-7 and virus nuclic acid among renal transplant patients in Khartoum state.
Method:
This was descriptive study in which serum specimens were collected from 95patient(72male,27 female)- and investigated for HHV-7 DNA using Nested PCR The study group age ranged from 20 to 80years old.
Results: All the samples were negative for HHV-7.
Conclusion:
HHV-7 was not documented in renal transplant patients. Further study should be done.
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