Molecular Detection of Human Herpes virus type 7 (HHV-7) among Renal Transplant Patients in Khartoum State, Sudan

Authors(2) :-Hala Siddig, Khalid A Enan

Background:

Human herpesvirus 7 (HHV-7) is one of eight known members of the Herpesviridae family that infects humans. HHV-7is a member of Betaherpesviridae, a subfamily of the Herpesviridae that also includes HHV-6 and Cytomegalovirus (HHV-5 or HCMV).[1] HHV-7 often acts together with HHV-6, and the viruses together are sometimes referred to by their genus, Roseolovirus. HHV-7 was first isolated in 1990 from CD4+ T cells taken from peripheral blood lymphocytes. This study was carried out to detect the HHV-7 and virus nuclic acid among renal transplant patients in Khartoum state.

Method:

This was descriptive study in which serum specimens were collected from 95patient(72male,27 female)- and investigated for HHV-7 DNA using Nested PCR The study group age ranged from 20 to 80years old.

Results:   All the samples were negative for HHV-7.

Conclusion:

HHV-7 was not documented in renal transplant patients. Further study should be done.

Authors and Affiliations

Hala Siddig
Department of Microbiology, Faculty of Medical Laboratories, Al Neelain University, Khartoum, Sudan
Khalid A Enan
Department of Virology Central Laboratory - The Ministry of Higher Education and Scientific Research, Khartoum, Sudan

Human herpes Viruses type 7(HHV-7).

  1. Epidemiology and Infection (Cambridge University Press) Jump up "Other Herpesviruses: HHV-6, HHV-7, HHV-8, HSV-1 and -2, VZV"American Journal of Transplantation (Blackwell Munksgaard)4 Suppl 10: 66–712004"Development of a PCR system for porcine cytomegalovirus detection and determination of the putative partial sequence of its DNA polymerase gene"123 (1): 177–180doi:10.1017/S0950268899002599PMC 2810741PMID 10487654.
  2. J Ongradi, JoZsef; Kovesdi, Valeria; Kovats, Enik? (2010)"Az emberi 7-es herpeszvírus"Orvosi Hetilap (in Hungarian):
  3. JI.; Fahle, G.; Kemp, MA.; Apakupakul, K.; Margolis, TP(2010)"Human Herpesvirus 6-A, 6-B and 7 in Vitreous Fluid Samples"Journal of Medical Virology 82
  4. Nicholas, John (September 1996)"Determination and analysis of the complete nucleotide sequence of human herpesvirus 7" (PDF)
  5. Cecile (January 2, 2008)Hirsch, Martin S; McGovern, Barbara H, eds"Human herpesvirus 7 infection"UpToDate
  6. Clark, DA; Freeland, ML; MacKie, LK; Jarrett, RF; Onions, DE (1993)"Prevalence of antibody to human herpesvirus 7 by age"The Journal of Infectious Diseases
  7. Suga, S; Yoshikawa, T; Nagai, T; Asano, Y (1997)"Clinical features and virological findings in children with primary human herpesvirus 7 infection".
  8. Clark, DA; Kidd, IM; Collingham, KE; Tarlow, M; Ayeni, T; Riordan, A; Griffiths, PD; Emery, VC; Pillay, D (1997)"Diagnosis of primary human herpesvirus 6 and 7 infections in febrile infants by polymerase chain reaction"

Publication Details

Published in : Volume 4 | Issue 4 | March-April 2018
Date of Publication : 2018-04-30
License:  This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) : 873-875
Manuscript Number : IJSRSET1844332
Publisher : Technoscience Academy

Print ISSN : 2395-1990, Online ISSN : 2394-4099

Cite This Article :

Hala Siddig, Khalid A Enan, " Molecular Detection of Human Herpes virus type 7 (HHV-7) among Renal Transplant Patients in Khartoum State, Sudan, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 4, pp.873-875, March-April-2018.
Journal URL : http://ijsrset.com/IJSRSET1844332

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