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An Optimization Method for Quantifying Magnetization Vectors in Magnetic Resonance Measurements

Authors(3):

Leila Borvayeh, Mohammad Sabati, Raouf Mbarki
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There are increasing interests in quantitative magnetic resonance (MR) measurement techniques for a variety of experimental physics and clinical applications. Recently methods for quantification of local nuclei magnetization magnitude, M0, and its longitudinal relaxation time (T1) have been proposed. An efficient method for measuring T1 values is based on acquiring two spoiled gradient-recalled echo (SPGR) data sets in steady states with different radiofrequency (RF) excitation flip angles, which has also been extended, with additional acquisitions, to obtain M0 values representing the object’s proton density. Several factors, including inaccurate flip angles due to inhomogeneity of the exciting RF magnetic fields and low signal-to-noise ratios (SNR) may negatively affect the accuracy of this method and produce systematic errors in the T1 and M0 estimations. In this paper, a modified dual-acquisition method based on an optimization of the SPGR MR sequence formulism is presented for reliable M0 and its actual flip angle (i.e., magnetization vector, M) measurements with a high spatial resolution and a relatively short experimental time. The optimal nominal flip angles for M0 measurements and the optimal repetition times for estimation of the RF excitation angles are found analytically and numerically using the SPGR MR sequence. The proposed method can measure the magnetization vectors with an isotropic spatial resolution of 1×1×1 mm3 of a large 3D object in less than 5 minutes.

Leila Borvayeh, Mohammad Sabati, Raouf Mbarki

Optimization, Magnetic Resonance (MR), Nuclei Magnetization Vector, Quantitative Analysis, MR Data Acquisition, Longitudinal Relaxation Time, Flip Angle.

  1. Carr HYSteady-state free precession in nuclear magnetic resonancePhys Rev 1958; 112: 1693– 1701.
  2. Oppelt A, Graumann R, Barfuss H, Fischer H, Hartl W, Shajor WFISP — a new fast MRI sequenceElectromedica 1986; 54: 15-8.
  3. Scheffler K, Lehnhardt SPrinciples and applications of balance SSFP techniquesEur Radiol2003; 13: 2409-18
  4. Leupold J, Hennig J, Scheffler KAlternating repetition time balanced steady state free precessionMagn Reson Med 2006; 55: 557-65.
  5. Hargreaves BA, Vasanawala SS, Nayak KS, Hu BS, Nichimura DGFat-suppressed steady-state free precession imaging using phase detectionMagn Reson Med 2003; 50: 210-3.
  6. Absil J, Denolin V, Metens TFat attenuation using a dual steady-state balanced-SSFP sequence with periodically variable flip anglesMagn Reson Med 2006; 55: 343-51.
  7. Deoni SC, Rutt BK, Peters TMRapid combined T1 and T2 mapping using gradient recalled acquisition in the steady stateMagn Reson Med 2003;49(3):515–26.
  8. Preibisch C, Deichmann RT1 mapping using spoiled FLASH-EPI hybrid sequences and varying flip anglesMagn Reson Med 2009;62(1):240–6.
  9. Helms G, Dathe H, Dechent PQuantitative FLASH MRI at 3 T using a rational approximation of the Ernst equationMagn Reson Med 2008;59(3):667–72.
  10. Neeb H, Zilles K, Shah NJA new method for fast quantitative mapping of absolute water content in vivoNeuroimage 2006;31(3):1156–68.
  11. Sabati M, Maudsley AAFast and high-resolution quantitative mapping of tissue water content with full brain coverage for clinically-driven studiesMagn Reson Imaging 2013;31(10):1752-59.
  12. Zong M1, Yan C, Lu L, Shi HB, Yu RBFeasibility of Dual Flip Angle-Based Fast 3-Dimensional T1 Mapping for Delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Cartilage of the Knee: A Histologically Controlled StudyJ Comput Assist Tomogr2016;40(3):442-6.
  13. Sabati M, Maudsley AAClinically-driven fast and high-resolution mapping of T1, M0, and B1 with whole brain coverageProc 18th ISMRMStockholm, Sweden; 2010p2317.
  14. Volz S, Noth U, Deichmann RCorrection of systematic errors in quantitative proton density mappingMagn Reson Med 2012;68(1):74–85.
  15. Neeb H, Ermer V, Stocker T, Shah NJFast quantitative mapping of absolute water content with full brain coverageNeuroimage 2008;42(3):1094–109.
  16. Johanson CE, Duncan 3rd JA, Klinge PM, Brinker T, Stopa EG, Silverberg GDMultiplicity of cerebrospinal fluid functions: new challenges in health and diseaseCerebrospinal Fluid Res 2008;5:10
  17. Gasparovic C, Neeb H, Feis DL, Damaraju E, Chen H, Doty MJ, South DM, Mullins PG, Bockholt HJ, Shah NJQuantitative spectroscopic imaging with in situ measurements of tissue water T1, T2, and densityMagn Reson Med 2009;62(3):583–90.
  18. Volz S, Noth U, Deichmann RCorrection of systematic errors in quantitative proton density mappingMagn Reson Med 2012;68(1):74–85.
  19. Cordes D, Yang Z, Zhuang X, Sreenivasan K, Mishra V, Hua LHA new algebraic method for quantitative proton density mapping using multi-channel coil dataMed Image Anal2017; 40:154-171
  20. Voigt T, Nehrke K, Doessel O, Katscher UT1 corrected B1 mapping using multi-TR gradient echo sequencesMagn Reson Med 2010;64(3):725–33.
  21. Yarnykh VLActual flip-angle imaging in the pulsed steady state: a method for rapid three-dimensional mapping of the transmitted radiofrequency fieldMagn Reson Med 2007;57(1):192–200.
  22. Warntjes JB, Dahlqvist O, Lundberg PNovel method for rapid, simultaneous T1, T*2, and proton density quantificationMagn Reson Med 2007;57(3):528–37.
  23. Meyers SM, Kolind SH, MacKay ALSimultaneous measurement of total water content and myelin water fraction in brain at 3T using a T2 relaxation based methodMagn Reson Imaging2017;37(4):187-194.

Publication Details

Published in : Volume 4 | Issue 8 | May-June - 2018
Date of Publication Print ISSN Online ISSN
2018-06-30 2395-1990 2394-4099
Page(s) Manuscript Number   Publisher
162-169 IJSRSET18487   Technoscience Academy

Cite This Article

Leila Borvayeh, Mohammad Sabati, Raouf Mbarki, "An Optimization Method for Quantifying Magnetization Vectors in Magnetic Resonance Measurements", International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 8, pp.162-169, May-June-2018.
URL : http://ijsrset.com/IJSRSET18487.php