Invitro-Anti Inflammatory and Anti Oxidant Activity of Euphorbia Nivulia

Authors

  • S. Gopi Krishnan  Department of Pharmacology, S. A. Raja Pharmacy College, Vadakkangulam, Tirunelveli Dist, Tamilnadu, India
  • Ajith A. P  Department of Pharmacology, S. A. Raja Pharmacy College, Vadakkangulam, Tirunelveli Dist, Tamilnadu, India
  • Renish C  Department of Pharmacology, S. A. Raja Pharmacy College, Vadakkangulam, Tirunelveli Dist, Tamilnadu, India
  • Duraiselvan S  Department of Pharmacology, S. A. Raja Pharmacy College, Vadakkangulam, Tirunelveli Dist, Tamilnadu, India
  • Subash Maruthu Pandian K  Department of Pharmacology, S. A. Raja Pharmacy College, Vadakkangulam, Tirunelveli Dist, Tamilnadu, India

Keywords:

Euphorbia Nivulia,Anti inflammatory, Anti oxidant.

Abstract

The drug discovery is very important Process. At the time of invention of new molecule of there is necessity of related fields like medicine, bio technology, chemistry and pharmacology. Plant remains the most common source of for a drug. In recent Years, the Production of natural products are increased in pharmaceutical companies due to minimal side effects. Herbal medicines are the oldest remedies known to mankind. India has one of the well known histories for the use of medicinal herbs(1). The present study was to evaluate the In-Vitro Anti Inflammatory and Anti Oxidant activity of Euphorbia Nivulia , (family: Euphorbiaceae)in various exracts. Anti inflammatory activity was studied using albumin denaturation assay , membrane stabilization assay at different concentrations. Aspirin was used as standard drug & anti oxidant activity was studied by DPPH radical scavenging activity by photometric assay using Rutin as standard. Results showed that the present study indicates that phytochemicals present in Euphorbia nivulia in various extracts may be responsible for Anti inflammatory and Anti oxidant activity.

References

  1. Amer jamalpoor, H.C.Satheesh, in vivo evaluation of genotoxic effects of euphorbia nivulia buch on mice bone marrow cells using chromosomal aberration test and micro nucleus assay. International journals of pharma research & review , Jan 2014;3 (1):28-33.
  2. Mohammad shahadat hossain, in vitro thrombolytic and anti inflammatory activity of swertia chirata ethanolic extract, journal of pharmacognosy and phytochemistry,ISSN 2278-4136.
  3. Ayurvedic pharmacopoeia, Ist edition Government of India.
  4. Mizushima Y and kobayashi M, Interaction of anti inflammatory drugs with serum proteins, especially with some biologically active proteins.J of Pharma pharmacol,1968;20;169-173.
  5. Aliyu, a.b.,Ibrahim, M.A.,Ibrahim, H.,Musa, A.M.,Lawal, A.Y.Oshanimi, departments of chemistry, 2 biochemistry,3 pharmaceutical and medicinal chemistry, ahmadu bello university, zaria-nigeria, Free radical scavenging and total antioxidant capacity of methanol extract of Ethulia conyzoides growing in Nigeria, Romanian Biotechnological Letters, Vol. 17, No. 4, 2012.

International Journal of Scientific Research in Science, Engineering and Technology

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Published

2018-06-30

Issue

Volume 4, Issue 8, May-June-2018

Section

Research Articles

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How to Cite

[1]
S. Gopi Krishnan, Ajith A. P, Renish C, Duraiselvan S, Subash Maruthu Pandian K, " Invitro-Anti Inflammatory and Anti Oxidant Activity of Euphorbia Nivulia , International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 8, pp.443-446, May-June-2018.