Synthesis, Spectral and Antimicrobial Study of Cd (II) Complexes and Heterocyclic base Adducts Derived from N (4) Phenyl Thiosemicarbazone

Authors

  • Dr. J. R. Gujarathi  Associate Professor Department of Chemistry, Pratap College, Amalner, Maharashtra, India

Keywords:

Metal Salts, Bioactivemetalcomplexes, Antimicrobial Activity, MIC.

Abstract

The synthesis and characterization, spectroscopic, and biological studies of 5-chloro-2-hydroxy acetophenone N (4) phenyl thiosemicarbazone and its complexes with cadmium (II) chloride are reported here. The thiosemicarbazone was synthesized by condensation of appropriate ketone and N (4) phenyl thiosemicarbazide. The reactions were carried out in the presence of sulfuric acid. The ligand,complex and adducts were characterized by means of Elemental analysis,ESI-MS, Fourier Transform Infrared (FT-IR) spectroscopy, Nuclear Magnetic Resonance (1HNMR and 13CNMR) spectroscopy magnetism and conductivity. The metal complexes and their corresponding thiosemicarbazone were tested against bacterial parasites. It was found that the cadmium complexes synthesized are more biologically active then their corresponding thiosemicarbazone.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2018-01-30

Issue

Volume 4, Issue 1, January-February-2018

Section

Research Articles

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How to Cite

[1]
Dr. J. R. Gujarathi, " Synthesis, Spectral and Antimicrobial Study of Cd (II) Complexes and Heterocyclic base Adducts Derived from N (4) Phenyl Thiosemicarbazone, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 1, pp.1609-1616, January-February-2018.