Applications of Hyphenated Analytical Techniques to Pharmaceutical Drug Analysis : A Review

Authors

  • Ratnakar Hole  Glenmark Research Center, Mahape, New Mumbai, Maharashtra, India
  • Vinod Lohakane  Birla College of Arts, Commerce & Science, Kalyan-West, Maharashtra, India
  • Sandesh Jaybhaye  Birla College of Arts, Commerce & Science, Kalyan-West, Maharashtra, India
  • Rajesh Dwivedi  Glenmark Research Center, Mahape, New Mumbai, Maharashtra, India
  • Achyut Munde  Milind College of Science, Aurangabad, Maharashtra, India

Keywords:

Analytical tools, Hyphenated techniques, Drugs analysis, Pharma Drugs

Abstract

As far analytical evaluations are concerned, today's advanced pharmaceutical organizations are facing increased number of challenges starting from raw materials right upto the finished product. The challenges are related to the accuracy, sensitivity, ease of laboratory demands, the purity, composition and performance of various drugs. Nowadays there is a vast array of scientific techniques available to the analytical scientists that enable this characterization. But the available analytical techniques are lacking to fulfill the increased demand of pharmaceutical analysis. In such contradictory environment, hyphenated technique had opened window of opportunities to the analytical scientists. Hyphenated techniques refer to combination of two or more analytical techniques to characterize the pharmaceutical drugs. These hyphenated techniques offer shorter analysis time, higher degree of automation, higher sample throughput, better reproducibility, reduction of contamination because it is a closed system, Enhanced combined selectivity and therefore higher degree of information. This review discusses the current trends in analytical evaluations of various types of materials which will provide unique path to the researchers to move a step forward.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2018-02-28

Issue

Volume 5, Issue 4, January-February-2018

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Research Articles

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How to Cite

[1]
Ratnakar Hole, Vinod Lohakane, Sandesh Jaybhaye, Rajesh Dwivedi, Achyut Munde, " Applications of Hyphenated Analytical Techniques to Pharmaceutical Drug Analysis : A Review, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 5, Issue 4, pp.112-121, January-February-2018.