Manufacture and Determination of Absorbent in Bolus Radiotherapy Based On Alginate Using of 8 MeV and 10 MeV Energy

Abstract

Bolus radiotherapy have been created by using material of mixture a silicone rubber as matrix and alginate powder as a filler through chemical solution deposition methods with variation of composition silicone rubber: alginate powder: catalyst (99 : 0 : 1)%wt, (80: 19: 1)%wt, (80: 18: 2)%wt, (80: 17: 3)%wt, (80:16: 4)%wt and (80: 15: 5)%wt. The sample fabrication was done in two steps. The first step of alginate powder is mixed with a solution of rubber and catalyst silicon until homogeneous for 5 minutes with the wet mixing method. The second step of the powder which was homogeneously mixed was printed with glass mould measuring 11 x 11 x 1 cm3 with variations in thickness of 5 mm, 10 mm and 15 mm then dried at 300. Each bolus sample is already to be characterized which includes: physical properties (density, porosity, and water absorption), mechanical properties (tensile strength, elongation and modulus young) and performance (CT Number and absorbency dose). The characterization results showed that alginate powder: optimum rubber silicon ie (80: 19) wt% at a thickness of 15 mm resulted in a density value of 2.091 x 103 kg/m3, porosity of 9.82% and water absorption of 1.66%. Mechanical properties with tensile strength 3.37 MPa, elongation at 45.28% and modulus of elasticity of 0.816 MPa. Bolus radiotherapy performance properties relative electron density (RED) values or CT numbers of 1.25 resulted in surface absorbance doses of 8 MeV of 101% and 10 MeV of 108.01%. The results of bolus radiotherapy based on composite alginate powder reinforced by silicone rubber can be applied as a cancer therapy material to replace bolus from wax, and paraffin.