Comparative Analysis of a few Indian Medicinal Plants for their Antimicrobial and Antioxidant Properties

Authors

  • Kiran Kumar D. J.  Department of P.G. Studies and Research in Biotechnology, Government Science College, Bangalore, Karnataka, India
  • Bhanupriya H. J.   Department of P.G. Studies and Research in Biotechnology, Government Science College, Bangalore, Karnataka, India

DOI:

https://doi.org//10.32628/IJSRSET20718

Keywords:

ABTS radical, Antibacterial activity, Antifungal activity, Antioxidant activity, DPPH radical, Plant extracts

Abstract

Plant-derived substances have been used since antiquity for therapeutic and other purposes. The present study was undertaken to make a comparative analysis of antimicrobial and antioxidant properties of 8 medicinal plants, which are used in traditional medicine system. Methanolic extracts of Centella asiatica (leaves), Mentha piperita (leaves), Calotropis gigantean (leaves), Vitex nigundo (leaves), Bauhinia racemosus (leaves), Emblica officinalis (fruit), Bauhinia purpurea (leaves), Asperagus racemosus (stem) were tested for anti-microbial effects using the standard Agar Diffusion method. Antioxidant attributes of above extracts were studied by testing their ability to scavenge DPPH and ABTS radicles. Our results indicated that all tested extracts, with the exception of Bauhinia purpurea, were effective against E. Coli, while Candida albicans was only sensitive to Asperagus racemosus. Among tested extracts, Bauhinia racemosus was most potent in exhibiting radical scavenging activity. Our data provides rationale for exploitation of these plants for antimicrobial and antioxidant attributes.

References

  1. S. M. K. Rates, “Plants as source of drugs," Toxicon, vol. 39, no. 5, pp. 603-613, 2001, doi: 10.1016/S0041-0101(00)00154-9.
  2. A. K. Shakya, “Medicinal plants: Future source of new drugs," Int. J. Herb. Med., vol. 4, no. 4, pp. 59-64, 2016.
  3. H. Sies, “Oxidative stress: Oxidants and antioxidants," Exp. Physiol., vol. 82, no. 2, pp. 291-295, 1997, doi: 10.1113/expphysiol.1997.sp004024.
  4. D. M. Kasote, S. S. Katyare, M. V Hegde, and H. Bae, “Significance of Antioxidant Potential of Plants and its Relevance to Therapeutic Applications," vol. 11, 2015, doi: 10.7150/ijbs.12096.
  5. S. B. Rao, M. Jayanthi, R. Yogeetha, H. Ramakrishnaiah, and J. Nataraj, “Free radical scavenging activity and reducing power of Gnidia glauca (Fresen.) Gilg ARTICLE INFO ABSTRACT," J. Appl. Pharm. Sci., vol. 3, no. 6, pp. 203-207, 2013, doi: 10.7324/JAPS.2013.3634.
  6. D. M. Kasote, M. V. Hegde, and S. S. Katyare, “Mitochondrial dysfunction in psychiatric and neurological diseases: Cause(s), consequence(s), and implications of antioxidant therapy," BioFactors, vol. 39, no. 4, pp. 392-406, 2013, doi: 10.1002/biof.1093.
  7. V. Kamath, A. K. R. Joshi, and P. S. Rajini, “Dimethoate induced biochemical perturbations in rat pancreas and its attenuation by cashew nut skin extract," Pestic. Biochem. Physiol., vol. 90, no. 1, pp. 58-65, 2008, doi: 10.1016/j.pestbp.2007.07.007.
  8. D. Krishnaiah, R. Sarbatly, and R. Nithyanandam, “A review of the antioxidant potential of medicinal plant species," Food Bioprod. Process., vol. 89, no. 3, pp. 217-233, 2011, doi: 10.1016/j.fbp.2010.04.008.
  9. T. G. Shaikh S., Lochan R., Kaul P., “Beta lactamase Inhibitors from Indigenous Herbs and Spices.," Res. J. Pharm. Biol. Chem. Sci., vol. 5, no. 2, pp. 275-285, 2014.
  10. J. L. Ríos and M. C. Recio, “Medicinal plants and antimicrobial activity.," J. Ethnopharmacol., vol. 100, no. 1-2, pp. 80-4, Aug. 2005, doi: 10.1016/j.jep.2005.04.025.
  11. M. Balouiri, M. Sadiki, and S. K. Ibnsouda, “Methods for in vitro evaluating antimicrobial activity: A review," J. Pharm. Anal., vol. 6, no. 2, pp. 71-79, 2016, doi: 10.1016/j.jpha.2015.11.005.
  12. D. K. B. Runyoro, M. I. N. Matee, O. D. Ngassapa, C. C. Joseph, and Z. H. Mbwambo, “Screening of Tanzanian medicinal plants for anti-Candida activity," BMC Complement. Altern. Med., vol. 6, pp. 1-10, 2006, doi: 10.1186/1472-6882-6-11.
  13. U. Mabona, A. Viljoen, E. Shikanga, A. Marston, and S. Van Vuuren, “Antimicrobial activity of southern African medicinal plants with dermatological relevance: From an ethnopharmacological screening approach, to combination studies and the isolation of a bioactive compound," J. Ethnopharmacol., vol. 148, no. 1, pp. 45-55, 2013, doi: 10.1016/j.jep.2013.03.056.
  14. F. Nazzaro, F. Fratianni, L. De Martino, R. Coppola, and V. De Feo, “Effect of essential oils on pathogenic bacteria," Pharmaceuticals, vol. 6, no. 12, pp. 1451-1474, 2013, doi: 10.3390/ph6121451.
  15. B. Auddy et al., “Screening of antioxidant activity of three Indian medicinal plants, traditionally used for the management of neurodegenerative diseases," J. Ethnopharmacol., vol. 84, no. 2-3, pp. 131-138, 2003, doi: 10.1016/S0378-8741(02)00322-7.
  16. V. Rajkumar, G. Guha, and R. Ashok Kumar, “Antioxidant and anti-neoplastic activities of Picrorhiza kurroa extracts," Food Chem. Toxicol., vol. 49, no. 2, pp. 363-369, 2011.

International Journal of Scientific Research in Science, Engineering and Technology

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Published

2020-01-30

Issue

Volume 7, Issue 1, January-February-2020

Section

Research Articles

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How to Cite

[1]
Kiran Kumar D. J., Bhanupriya H. J. , " Comparative Analysis of a few Indian Medicinal Plants for their Antimicrobial and Antioxidant Properties, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 7, Issue 1, pp.73-79, January-February-2020. Available at doi : https://doi.org/10.32628/IJSRSET20718