Manuscript Number : IJSRSET207266
Chemistry and Biological Evaluation of Some New Triazolopyrimidine Derivatives Containing Isopropyl Group
Authors(2) :-Janaki H. Chauhan, Dr. Haresh K. Ram
An efficient Synthesis of a novel series of N,7-bis(substitutedphenyl)-4,7-dihydro-5-isopropyl-[1,2,4]triazolo-[1,5-a]pyrimidine-6-carboxamide (4a-j) was accomplished from N-(substituedphenyl)-4-methyl-3-oxopentanamide, 3-amino-1,2,4-triazole and different aldehyde reflex 20 min with DMF and then after the cooling product was obtained. All the recently synthesized compounds were characterized by the Mass, IR, 1H-NMR and mass spectroscopic techniques and by elemental analyses. The newly synthesized compounds were assessed for their antibacterial and antifungal activity.
Janaki H. Chauhan
3-amino-1,2,4-triazole N-(substituedphenyl)-4-methyl-3-oxopentanamide and DMF.
Publication Details
Published in :
Volume 6 | Issue 3 | May-June 2019 Article Preview
Tolani College of Arts & Science, Adipur, Gujarat, India
Dr. Haresh K. Ram
Tolani College of Arts & Science, Adipur, Gujarat, India
Date of Publication :
2019-05-30
License: This work is licensed under a Creative Commons Attribution 4.0 International License.
Page(s) :
390-396
Manuscript Number :
IJSRSET207266
Publisher : Technoscience Academy
Journal URL :
https://ijsrset.com/IJSRSET207266