Synthesis of Credible Fluoro Nitro Containg Novel Benzopyrimidi

Authors

  • Dr. J. R. Shukla  Department of Chemistry, Shri C.N.P.F Arts & D. N.Science College, Dabhoi, Gujarat, India
  • Vikas Chauhan  Asstanr Manager, Apothecon Pharmaceutical, Dabhasa, Gujarat, India

Keywords:

N-(substitutedphenyl)-3-oxobutanamides, 4-(4-(trifluoromethyl)-2-nitrophenoxy)benzaldehyde, 2-amino benzimidazole and DMF only refluxed.

Abstract

Synthesis of a series of N-(substituted phenyl)-2-methyl-4-(4-(4-(trifluoro methyl)-2-nitrophenoxy) phenyl)-1,4-dihydropyrimido[1,2-a] benzimidazole-3-carboxamide products (4a-j) was completed from 4-(4-(trifluoromethyl)-2-nitrophenoxy)benzaldehyde, N-(substitutedphenyl)-3-oxobutanamides and using 2-amino benzimidazole in DMF reflux for 24 hrs, the product obtained was isolated. So to the outstanding yield. The structures of the products were supported by FTIR, 1H NMR and mass spectral data.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2016-12-31

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Volume 2, Issue 6, November-December-2016

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Research Articles

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[1]
Dr. J. R. Shukla, Vikas Chauhan, " Synthesis of Credible Fluoro Nitro Containg Novel Benzopyrimidi, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 2, Issue 6, pp.747-753, November-December-2016.