Synthesis, Spectral, Thermal Stability and Antimicrobial Assay of Six Co-Ordinate Complexes of Fe (III) Derived from N (4) Thiosemicarbazone

Authors

  • Dr. J. R. Gujarathi  Associate Professor, Chemistry(Science), Pratap College, Amalner, Maharashtra, India

Keywords:

Metal Salts, Bioactivemetalcomplexes, Antimicrobialactivity.MIC.

Abstract

Fe (III) complexes have been synthesized by the reaction of  FeCl3with 5-chloro-2-hydroxy acetophenone methyl thiosemicarbazone in presence of heterocyclic bases like pyridine (py), α/β/γ-picoline. Thiosemcarbazone has been characterized by 13C, 1H NMR,ESI-MS aswell as IR, electronic spectra.Spectral and magnetic measurements indicatedOctahedral geometry for the six coordinate complexes. Thethiosemicarbazone and its Fe (III) complexeshave been found The metal complexes and their corresponding ligands were tested against bacterial parasites. It was found that the iron complexes synthesized are more biologically active then their corresponding thioemicarbazone.

References

  1. Dubey S N VaidB. K, Synth. React. Inorg. Met. Org. Chem., 21,19911299.
  2. HendawyA. M,. Kourashy E. G .ShanabM. M, Polyhedron, 111992 523.
  3. MarikuttyP. V, Ph. D Thesis, Calicut University, Kerala2002.
  4. Abdul JaleelU. C, Ph. D Thesis, Calicut University, Kerala2005.
  5. SyamalA . KalaK. S, Indian. J. Chem., 19A, 5 1980 488.
  6. Tez Can, Chim. Acta. Turk., 12 (2) 1984 376.
  7. SalamM. A, J. Bangladesh. Acad. Sci. 1992.
  8. SyamalA. and. SinghM. M, Indian J. Chem. Sect. A, 32 1993 42-48.
  9. HassanM. A,.KhalifaA. M. ShehataK. A, Bull. Soc. Chim. Belg.,104 (3) 1995 121.
  10. ZelentsovV. V, Russian J. Coord. Chem., 22, 9 1996 674.
  11. FehnA., Briel O. BeckW, Chem. Ber. Recl., 130 (10) 1997 1467
  12. MayadeviS.,.YusuffK. K Mohammed, Synth. React. Inorg. Met.Org. Chem., 27 (2) 1997 319
  13. NaikS., J. Indian. Coun. Chem. 15 (1) (2) 1998 7.
  14. Geary W.J., Coord. Chem. Rev, 1971, 7, 81.
  15. John R.P., Sreekanth A., Kurup M.R.P.,. Usman A,.Razakl.A. Fun H.-K.Spectrochim. Acta A 59 2003 1349.
  16. Nazimuddin M. Ali M.A., Smith F.E., Polyhedron 10 1991 327.
  17. Bermejo E. CarballoR., Castineiras A., Dominguez R. LibertaA. E.,Maichle-MossmerC.,WestD. X. ,Naturforsch Z.B: Chem. Sci. 54 1999 777.
  18. CastineirasA,. Bermejo E,WestD. X.,AckermanL.J., MartinezJ. V,.Ortega S. H.Polyhedron18 1999 1469.
  19. Naik A.D.,RevankarV.K.,Proc. Indian Acad. Sci (Chem. Sci.) 113 2001285.
  20. PhilipV.,Suni V.,KurupM.R.PPolyhedron 25 20061931.
  21. LiI.X.,Tang H.A., Yi-ZhiLi.,WangM.,Wang L.F., Xia C.G.J. Inorg.Biochem. 78 2000 167.
  22. John R.P., Sreekanth A., Rajakannan V., Ajith T.A., KurupM.R.P.,Polyhedron 23 2004 2549.
  23. Nakamoto K., Infrared and Raman Spectra of Inorganic and Coordinationcompounds, 5"'ed., Wiley, New York, 1997.
  24. Bindu P. Kurup M.R.P.,SatyakeerthyT.R.Polyhedron1.8 1999 321.
  25. West D.X.,Whyte A.C Sharif F.D.,Gabremedhin H., Liberta A.E. Trans.Met. Chem. 18 1993 238.
  26. Inskeep R.G., J. InorgNucl-Chem, 24 1962 763.
  27. Schilt A.A., Taylor R.C., J. Inorg. Nucl. Chem. 9 1959 217.
  28. Monoyama M., Inorganic ChimActa, 13 1975 5.
  29. Mohamed G.G., Nour-El Dien FA, El-Gamel E.A., J. Therm. Anal. Cal, 67 2002 135.
  30. Salmon S.A,Watts J.L,Cheryal A.J.Clin.Microbial,1995,2435.
  31. Shankar K.,Muralidhar Reddy P,Rohini R,Vadde Ravindra DerPharmacia Letter;1,2009,97

International Journal of Scientific Research in Science, Engineering and Technology

Downloads

Published

2017-12-31

Issue

Volume 3, Issue 8, November-December-2017

Section

Research Articles

License

Copyright (c) IJSRSET

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Dr. J. R. Gujarathi "Synthesis, Spectral, Thermal Stability and Antimicrobial Assay of Six Co-Ordinate Complexes of Fe (III) Derived from N (4) Thiosemicarbazone" International Journal of Scientific Research in Science, Engineering and Technology (IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 8, pp.1129-1136, November-December-2017.