Synthesis and Antimicrobial Evaluation of Novel Chalcones Bearing Coumarin Moiety

Authors

  • Bhavin Thaker  Department of Chemistry, Pacific College of Basic & Applied Sciences, Udaipur, Rajasthan, India
  • Kartik Vyas  Department of Chemistry, Sheth L.H. Science College, Mansa, Gujarat, India
  • Janak Shukla  Department of Chemistry, C. U. Shah Science College, Ahmedabad, Gujarat, India
  • Ramesh Patel  C.N.P.F Arts and D.N. Science College, Dabhoi, Gujarat, India
  • Kiran Nimavat  Department of Chemistry, Government Science College, Gandhinagar, Gujarat, India

Keywords:

Chalcones, Coumarin Moiety, Antibacterial Activity, Antifungal Activity

Abstract

Novel Chalcones bearing Coumarin moiety were synthesized by the reaction of 2-oxo-4-(piperazin-1-yl)-2H-chromene-3-carbaldehyde with different acetophenones in presence of piperidine. All the newly synthesized chalcones were characterized by different spectroscopic techniques and elemental analyses. All the compounds were evaluated for their antibacterial activity against S. aureus, E.coli and for their antifungal activity against C. albicans.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2017-08-31

Issue

Volume 3, Issue 5, July-August-2017

Section

Research Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Bhavin Thaker, Kartik Vyas, Janak Shukla, Ramesh Patel, Kiran Nimavat "Synthesis and Antimicrobial Evaluation of Novel Chalcones Bearing Coumarin Moiety" International Journal of Scientific Research in Science, Engineering and Technology (IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 5, pp.643-645, July-August-2017.