Serofrequency of Mumps Virus among Children with Type One Diabetes Mellitus Comparing to Control Group in Khartoum State

Authors

  • Abeya Salah Ibrahim  aculty of Medical Laboratory Sciences, Al Neelain University, Sudan
  • Wafa Ibrahim Elhag  Associate professor, Faculty of Medical Laboratory Sciences, Microbiology Department, Al Neelain University, Sudan
  • Nasr Mohamed Nasr  Assistant professor, Omdurman Ahlia University, Microbiology Department, Sudan
  • Mohamed Hussein Arbab  Assistant professor of medical Microbiology Omdurman Ahlia University, Sudan

Keywords:

Anti Mumps, Type I diabetes mellitus.

Abstract

Background and Objectives: Epidemiological studies suggested that Mumps pancreatitis may associated with subsequent development of type one diabetes mellitus (T1D). This study was aimed to detect sero frequency of Mumps virus among children with T1D mellitus comparing to control group in Khartoum state.
Methods: This was a descriptive case control study involve 90 children with T1D (Test group) and 90 healthy children (Control group) in Khartoum, patients aged between (1-5) years old, conducted in Omdurman Pediatric Teaching Hospital and Gaber Abo Eleiz Hospital - Khartoum State, Sudan, during February to September 2016. Mumps virus IgG for all participants was investigated using commercially available enzyme-linked immunosorbent assay (ELISA). Generated data were analyzed using SPSS and excel software programs.
Results: The results revealed that the frequency of Mumps IgG were 23 (25.6%) and 3 (3.3%) among patients and control group respectively, also shown statistically significant relationship between Mumps virus infection and T1D with P- value (0.048). 
Conclusion: The seropositivity of Mumps virus among children with type one diabetes mellitus is significantly detected, further workup is required to co relate and  confirmatory test and fellow up with large scale specimen is recommended.

References

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2018-02-28

Issue

Volume 4, Issue 1, January-February-2018

Section

Research Articles

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How to Cite

[1]
Abeya Salah Ibrahim, Wafa Ibrahim Elhag, Nasr Mohamed Nasr, Mohamed Hussein Arbab, " Serofrequency of Mumps Virus among Children with Type One Diabetes Mellitus Comparing to Control Group in Khartoum State, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 4, Issue 1, pp.239-243, January-February-2018.