Effectual direct synthesis of diversely substituted 4-aryl/alkyl coumarins by palladium catalyzed oxidative Suzuki–Miyaura coupling

Authors

  • Jaydip Rajpara  Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot, India
  • Arpit Radadia  Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot, India
  • Yogesh Naliapara  Chemical Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot, India

Keywords:

4-aryl/alkylcoumarins, Suzuki-Miyaura coupling, Palladium catalyst, Boronic acid or

Abstract

An effectual direct synthesis of 4-aryl/alkyl substituted coumarin was developed using a palladium-catalyzed oxidative Suzuki–Miyaura coupling reaction strategy. Use of Pd2(dba)3 in the presence of Na2CO3 in THF solvent was found to be the most effective reaction condition for excellent yield.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2017-10-31

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Volume 3, Issue 6, September-October-2017

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Research Articles

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[1]
Jaydip Rajpara, Arpit Radadia, Yogesh Naliapara "Effectual direct synthesis of diversely substituted 4-aryl/alkyl coumarins by palladium catalyzed oxidative Suzuki–Miyaura coupling" International Journal of Scientific Research in Science, Engineering and Technology (IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 3, Issue 6, pp.230-237, September-October-2017.