Synthesis and Biological Evaluation of Some New Acetyl Pyrazoline Derivatives of 3-Aryl-2-Isobutanoyl-N-Phenyl-Acrylamide

Authors

  • D. N. Joshi  Department of Chemistry, R.R.Mehta College of Science & C.L.Parikh college of Commerce Palanpur, Gujarat, India

Keywords:

3-Aryl-2-isobutanoyl-N-phenyl-acrylamide, Acetyl pyrazoles, Antimicrobial activities.

Abstract

The broad spectrums of pharmacological properties have been demonstrated by the pyrazole nucleus. Some new 1-Acetyl-5-aryl-3-isopropyl-4-[n-phenyl-aminocarbonyl]-4,5-dihydro-1H-pyrazoles.The pyrazoline derivatives of Type (1a-j) have been synthesized by the reaction of 3-Aryl-2-isobutanoyl-N-phenyl-acrylamide with hydrazine hydrate in glacial acetic acid. All the prepared compounds were characterized by their spectral (I.R., N.M.R., Mass) data and screened for their antimicrobial activities.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2014-12-30

Issue

Volume 1, Issue 1, -2014

Section

Research Articles

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How to Cite

[1]
D. N. Joshi, " Synthesis and Biological Evaluation of Some New Acetyl Pyrazoline Derivatives of 3-Aryl-2-Isobutanoyl-N-Phenyl-Acrylamide, International Journal of Scientific Research in Science, Engineering and Technology(IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 1, Issue 1, pp.169-173, -2014.