Hydroxyapatite integrated with Carboxymethyl cellulose and Agar-Agar/I-Carragenan biopolymer composites for antimicrobial investigations

Authors

  • Kiruthika T. S  PG and Research, Department of chemistry, Presidency College (Autonomous), Chennai, Tamil Nadu, India
  • Aravind Viswanath J  Department of Chemical Engineering, A.C. Tech, Anna University, Chennai, Tamil Nadu, India
  • Jaishankar V  PG and Research, Department of chemistry, Presidency College (Autonomous), Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.32628/IJSRSET229410

Keywords:

Biopolymer, Carboxymethyl Cellulose, n-hydroxyapatite, Bionanocomposite, antimicrobial.

Abstract

Biopolymer based composites have been extensively used as a promising materials for various biomedical applications such as scaffold preparation, drug delivery, etc. Hence, researchers have focused their attention on the development of novel biomaterials to cater the demand in the field of medicine. In this investigation, we report the preparation and characterisation of Carboxymethyl cellulose (CMC)/Agar-Agar/n-HAp and Carboxymethyl cellulose (CMC)/?-carragenan/n-HAp polymeric composites. The common biopolymer CMC used in this study was isolated from the plant source hemp as cellulose and then it was functionalized to carboxymethyl cellulose (CMC). The SEM images showed that the addition of nano hydroxyapatite induces considerable morphological changes in the surface and cross section of the composites. Thermal analysis was used to ascertain the thermal stability of the prepared materials. Further the antibacterial, antifungal, wound healing and anticancer efficiency of the composite films were evaluated and compared. The prepared bionanocomposites have potential therapeutic value for various biomedical applications.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2022-08-30

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Volume 9, Issue 4, July-August-2022

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Research Articles

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[1]
Kiruthika T. S, Aravind Viswanath J, Jaishankar V "Hydroxyapatite integrated with Carboxymethyl cellulose and Agar-Agar/I-Carragenan biopolymer composites for antimicrobial investigations" International Journal of Scientific Research in Science, Engineering and Technology (IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 9, Issue 4, pp.86-103, July-August-2022. Available at doi : https://doi.org/10.32628/IJSRSET229410