Chemosensors Based on Benzothiazole and Coumarin Platform
Keywords:
Coumarin, Benzothiazole, Fluorophores, Fluorescent ProbesAbstract
The development of methods for the translation of fluorophores into fluorescent probes continues to be a robust field for medicinal chemists and chemical biologists, Ideal responsive fluorescent probes are those that contain a fluorophore tethered to both a sensing unit, to ensure selectivity of response, and a targeting group, to control the sub-cellular localisation of the probe. Due to their high levels of sensitivity, fast response time, and technical simplicity, small molecule based fluorescent probes have been widely developed and applied to the detection of many biologically important analytes, in particular, fluorescent probes for biologically and/or environmentally important cations, anions, small neutral molecules, and biological macromolecules. This review highlights the advances in the development of fluorescent and/or colorimetric probes, based on coumarin and benzothiazole platform.
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