Synthesis and Antibacterial Evaluation of Pyrazole Integrated Oxadiazole Derivatives

Authors

  • Bhatt Jyotindra  Department of Chemistry, KSKV Kachchh University, Bhuj, Kutch, India
  • Hadiyal Ashvin  Department of Chemistry, KSKV Kachchh University, Bhuj, Kutch, India
  • Girin Baxi  Department of Chemistry, KSKV Kachchh University, Bhuj, Kutch, India
  • Ajay Rathod  Department of Chemistry, KSKV Kachchh University, Bhuj, Kutch, India

DOI:

https://doi.org/10.32628/IJSRSET23103206

Keywords:

Pyrazole, Oxadiazole, pyridine, Antibacterial.

Abstract

Pyrazole, Pyridine, and oxadiazole are important scaffolds because of having medicinal applications like anticonvulsant, hypoglycemia, molluscicidal, stimulant, and anticancer, etc. At present, to achieve a highly potent molecule we have synthesized a novel series of pyrazole bearing 1,3,4-oxadiazole heterocycles 4a–o (1-(3,5-substituted-diphenyl-4,5-dihydro-1H-pyrazol-1-yl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)ethan-1-one) were and characterized by mass spectroscopy, 1H and 13C NMR spectroscopy, and Infrared spectroscopy. All synthesized compounds were evaluated against gram-positive and gram-negative bacterial strains.

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International Journal of Scientific Research in Science, Engineering and Technology

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Published

2023-08-30

Issue

Volume 10, Issue 4, July-August-2023

Section

Research Articles

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How to Cite

[1]
Bhatt Jyotindra, Hadiyal Ashvin, Girin Baxi, Ajay Rathod "Synthesis and Antibacterial Evaluation of Pyrazole Integrated Oxadiazole Derivatives" International Journal of Scientific Research in Science, Engineering and Technology (IJSRSET), Print ISSN : 2395-1990, Online ISSN : 2394-4099, Volume 10, Issue 4, pp.244-252, July-August-2023. Available at doi : https://doi.org/10.32628/IJSRSET23103206