Identification and Antidiabetic Activity of Coumarin in Aegle Marmelos

Abstract

Diabetes mellitus, one of the primary metabolic illnesses, affects 2.8% of people worldwide and is predicted to rise to 5.4% by 2025. The use of herbal treatments in modern, high-tech medicine is expanding, as they have long been considered as a highly effective source of medication. In light of the aforementioned factors, the current review presents profiles of the plant Aegle marmelos, which has hypoglycemic properties. These profiles are based on literature sources from numerous databases, and they are properly categorized according to the parts used, the method of lowering blood sugar (insulin mimetic or activity of insulin secretagogues), and the active phytoconstituents that have insulin mimetic activity. According to the review, plants with hypoglycemic potential primarily belong to the Rutaceae family. As a result, the analysis largely concludes that the presence of coumarins and other elements that demonstrate a decrease in blood glucose levels is what gives Aegle marmelos its antidiabetic properties. The research also covers how these plants' active ingredients can be used to manage diabetes mellitus.