Biological Synthesis of Copper Nanoparticles using Tinospora cardifolia Extract and their Antioxidant Activity
DOI:
https://doi.org/10.32628/IJSRSET241475Keywords:
Antioxidant, Nano, Roots, Copper, BioAbstract
In the current study investigates the antioxidant properties of Tinospora Cardifolia extract and the biological production of copper nanoparticles. Tinospora cordifolia is used in this work to produce copper nanoparticles, which are then characterized by FTIR, XRD, and TEM analysis. The plant extract was prepared from the leaves of Tinospora cordifolia. The test procedures for antibacterial, phytochemical, and antioxidant properties are also explained. The results were collected and statistically analyzed. Tinospora cordifolia extract was used as a reducing agent in the synthesis of CuNPs using the chemical reduction procedure because of its high phenolic and flavonoid content as well as its antibacterial and anti-inflammatory qualities. The goal of this effort was to find a more ecologically friendly way to produce copper nanoparticles in order to give pharmacological evidence against the antioxidant activity. Further study and in vivo studies are necessary to further understand the potential phenolic and flavonoid compounds found in Tinospora cordifolia's leaves, bark, and roots.
Downloads
References
Ananda Murthy HC, Desalegn T, Kassa M, et al. “Synthesis of Green copper nanoparticles using medicinal plant Hagenia abyssinica (Brace) JF. Gmel. Leaf extract: Antimicrobial properties. J Nanomater. 2020;2020. Article ID 3924081:12. doi: 10.1155/ 2020/3924081
Bishayi B, Roychowdhury S, Ghosh S, Sengupta M. Hepatoprotective and immunomodulatory properties of Tinospora cordifolia in CCl4intoxicated mature albino rats. J Toxicol Sci 2002; 27(3):139–146.
Dass Prakash M.V., Shobana Sampath, K. Amudhaa, Ahmed Nadeem, Bruno Silvester Lopes, B. Durga and Saravanan Muthupandian. Eco-friendly green synthesis of copper nanoparticles from Tinospora cordifolia leaves: optical properties with biological evaluation of anti-microbial, anti-inflammatory and anti-oxidant applications. Materials Technology 2023, 38(1), Article ID 2247908 doi: 10.1080/10667857.2023.2247908
Gangwar M, Gautam MK, Sharma AK, et al. Antioxidant capacity and radical scavenging effect of polyphenol rich Mallotus philippenensis fruit extract on human erythrocytes: an in vitro study. Sci World J. 2014;2014:1–12. doi: 10.1155/2014/279451
Gholami M, Azarbani F, Hadi F, et al. Eco-Friendly Synthesis of Copper Nanoparticles Using Mentha Pulegium Leaf Extract: Characterisation, Antibacterial and Cytotoxic Activities. Mater Technol. 2022;37:1523–1531. doi: 10.1080/10667857. 2021.1959214
Jagetia GC, Rao SK. Evaluation of cytotoxic effects of dichloromethane extract of Guduchi (Tinospora cordifolia Miers ex Hook F & Thoms) on cultured HeLa cells. Evid Based Complement Altern Med 2006; 3(2):267–272.
Jayaseelan C, Rahuman AA, Rajakumar G, et al. Synthesis of pediculocidal and larvicidal silver nanoparticles by leaf extract from heartleaf moonseed plant, Tinospora cordifolia Miers. Parasitol Res. 2011;109 (1):185–194. doi: 10.1007/s00436-010-2242-y
Kalikar MV, Thawani VR, Varadpande UK, Sontakke SD, Singh RP, Khiyani RK. Immunomodulatory effect of Tinospora cordifolia extract in human immuno-deficiency virus positive patients. Ind J Pharmacol 2008; 40(3):107–110.
Kapur P, Jarry H, Wuttke W, Pereira BM, Seidlova-Wuttke D. Evaluation of the antiosteoporotic potential of Tinospora cordifolia in female rats. Maturitas 2008; 59(4):329–338.
Kedare SB, Singh RP. Genesis and development of DPPH method of antioxidant assay. J Food Sci Technol. 2011;48(4):412–422. doi: 10.1007/s13197- 011-0251-1
Md M R, Md B I, Biswas M, et al. In vitro antioxidant and free radical scavenging activity of different parts of Tabebuia pallida growing in Bangladesh. BMC Res Notes. 2015;8(1):621. doi: 10.1186/s13104-015-1618-6
Nadkarni KM, Nadkarmi AK. Indian Materia Medica. Ed 3, Vol. 1, Mumbai: M/s Pop Prak Priv Lmt, 1976.
Nayampallie S, Ainapure SS, Nadkarni PM. Study of antiallergic and bronchodilator effects of Tinospora cordifolia. Ind J Pharm 1982; 14:64–66.
Panchabhai TS, Ambharkhane SV, Joshi AS, Samant BD, Rege NN. Protective effects of Tinospora cordifolia, Phyllantus emblica and their combination against antitubercular drugs induced hepatic damage: an experimental study. Phytother Res 2008; 22(5):646-650.
Selvam K, Sudhakar C, Govarthanan M, et al. Eco-friendly biosynthesis and characterization of silver nanoparticles using Tinospora cordifolia (Thunb.) Miers and evaluate its antibacterial, antioxidant potential. J Radiat Res Appl Sci. 2017;10(1):6–12. doi: 10.1016/j.jrras.2016.02.005
Sharma P, Pant S, Dave V, et al. Green synthesis and characterization of copper nanoparticles by Tinospora cardifolia to produce nature-friendly copper nano-coated fabric and their antimicrobial evaluation. J Microbiol Methods. 2019;160:107–116. doi: 10.1016/j.mimet.2019.03.007
Sharma P, Pant S, Poonia P, et al. Green synthesis of colloidal copper nanoparticles capped with Tinospora cordifolia and its application in catalytic degradation in textile dye: an ecologically sound approach. J Inorg Organomet Polym Mater. 2018;28(6):2463–2472. doi: 10.1007/s10904-018- 0933-5
Sharma SK, Singh AP. In vitro antioxidant and free radical scavenging activity of nardostachys jatamansi DC. J Acupunct Meridian Stud. 2012;5(3):112–118. doi: 10.1016/j.jams.2012.03.002
Shruthi Devi R, Jeevitha M, Preetha S, Rajeshkumar S. Free Radical Scavenging Activity of Copper Nanoparticles Synthesized from Dried Ginger. Journal of Pharmaceutical Research International. 2020 Aug 26;1–7.
Singh K, Panghal M, Kadyan S, et al. Antibacterial activity of synthesized silver nanoparticles from Tinospora cordifolia against multi drug resistant strains of Pseudomonas aeruginosa isolated from burn patients. J Nanomed Nanotechnol. 2014;5(2): doi: 10.4172/2157-7439.1000192
Singh SS, Pandey SC, Srivastava S, et al. Chemistry and Medicinal Properties of Tinospora cordifolia (Guduchi). Indian Journal of Pharmacology. 2003;35:83–91.
Upadhyay, Neha & Ganaie, & Agnihotri, Rajneesh & Sharma, Rajendra. Free Radical Scavenging Activity of Tinospora cordifolia (Willd.) Miers.” Journal of Pharmacognosy and Phytochemistry. 2014, 3. 63-69.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 International Journal of Scientific Research in Science, Engineering and Technology
This work is licensed under a Creative Commons Attribution 4.0 International License.
